the mark IIc+, III, and IV's are some of my favorite amps because with that 5 band and the presence knob, you can make that thing sound awesome with a 1x12, 2x12, or a 4x12.
i found "my sound" with my mark IV on a EV thiele, then i went to my band rehersal place and through it through my c90 loaded metal grill boogie 4x12 and i bumped the presence down a tad and had a killer lead tone right away with pretty much the same settings.