My settings won't do much good if you're not running my speakers, and guitar, ect...
I can give you some tip tho. Try to get your bass from the graphic. Run the bass knob somewhere around 9:00-11:00. You can get more perceived bass by dropping the 750 slider a bit. I think the bright is to much on the IV mode, so I keep it on normal. It's fine for the 2C+ IMO. Keep treble higher than presence for clear bite, and not hash. I bump the 2200, and leave the 6600 in the middle.
The key is to balance the 3 channels volume wise, and then tune from there. Higher volume of one or another will make it sound like others have more or less freqs when they might be fine. That's the Fletcher Munson effect. http://en.wikipedia.org/wiki/Fletcher%E2%80%93Munson_curves
