Yes you can, just pull the two outer tubes or the inner tubes, and take one rec tube out for each pair of power tubes.
Ive run mine with 2 power tubes and 1 rec tube.
If its all about volume you really wont notice a huge difference, it does sound a bit thinner to my ears, but volume wise your not going to knock it down that much.
If you want to kill volume I would suggest engaging the effects loop and use the volume on the effects loop to control your overall volume, I would do this before pulling tubes. Unless you are playing hard core metal, you should be able to get some good tones out this way without splitting your ear drums, Ive done this for years with mine.
Good Luck